• Bone graft substitutes and bone morphogenetic proteins for spine surgery 
• Cervical decompression with or without fusion 
  
• Cervical disc arthroplasty 
  
• Hip arthroplasty 
  
• Hip arthroscopy and open procedures 
• Knee arthroplasty
  
• Knee arthroscopy and open procedures 
• Lumbar disc arthroplasty 
• Lumbar discectomy, foraminotomy, and laminotomy 
• Lumbar fusion and treatment of spinal deformity (including scoliosis and kyphosis) 
  
• Lumbar laminectomy 
• Meniscal allograft transplantation of the knee 
• Shoulder arthroplasty 
• Shoulder arthroscopy and open procedures 
• Treatment of osteochondral defects 
• ​Vertebroplasty/Kyphoplasty 

Interventional pain manageme​​nt services

• Epidural Injection Procedures and Diagnostic Selective Nerve Root Blocks
  
• Paravertebral Facet Injection/Nerve Block/Neurolysis 
• Regional Sympathetic Nerve Block 
• Sacroiliac joint injections 
• ​Implanted spinal cord stimulators 

Reconstructive procedures and poten​​tially cosmetic procedures 

• Blepharoplasty/ptosis repair
  
  15820, 15821, 15822, 15823, 67900, 67901, 67902, 67903, 67904, 67906, 67908, 67909​ 


• ​Bone graft, genioplasty and mentoplasty
  
  21120, 21121, 21122, 21123
   
• Breast Reconstruction
  
  11920, 11921, 11922, 11970, 11971, 15271, 15272, 15769, 15771, 15772, 15773, 15774, 15777, 19350, 19355, 19357, 19361, 19364, 19367, 19368, 19369, 19380, Q4100, Q4107, Q4116, Q4130, Q4142, Q4143, S2066, S2067, S2068
   
• Breast Reduction
  
  15877, 19318
   
• Breast Augmentation/Mammoplasty
  
  19325​
   
• Breast Mastopexy
  
  19316
   
• Insertion of Breast Implants
  
  19340, 19342, 19396
   
• Removal of Breast Implants
  
  19328, 19330, 19370, 19371
   
• Canthopexy/Canthoplasty
  
  21280, 21282, 67950
   
• Cervicoplasty
  
  15819
   
• Chemical peels
  
  15788, 15789, 15792, 15793​
   
• Dermabrasion
  
  15780, 15781, 15782, 15783
   
• Excision of excessive skin and/or subcutaneous tissue
  
  15830, 15832, 15833, 15834, 15835, 15836, 15837, 15838, 15839
   
• Gender reassignment surgery
  
  11960, 19303, 53430, 54125, 54400, 54401, 54405, 54520, 54660, 54690, 55175, 55180, 57106, 57110, 58150, 58180, 58260, 58262, 58275, 58290, 58291, 58541, 58542, 58543, 58544, 58550, 58552, 58553, 58554, 58570, 58571, 58572, 58573, 58720
   
• Genetically and bio-engineered skin substitutes for wound care
  
  A2001, A2002, A2004, A2007, A2008, A2009, A2010,​ A2011, A2012, A2013, A2014, A2015, A2016, A2018, A2019, A2021, A2022, A2023, A2024, A2025, Q4100, Q4101, Q4102, Q4103, Q4104, Q4105, Q4106, Q4107, Q4108, Q4110, Q4111, Q4113, Q4114, Q4115, Q4117, Q4118, Q4121, Q4122, Q4123, Q4124, Q4126, Q4127, Q4128, Q4132, Q4133, Q4134, Q4135, Q4136, Q4137, Q4139, Q4140, Q4141, Q4145, Q4146, Q4147, Q4148, Q4149, Q4151, Q4152, Q4153, Q4154, Q4155, Q4156, Q4157, Q4158, Q4159, Q4160, Q4161, Q4162, Q4163, Q4164, Q4165, Q4166, Q4167, Q4168, Q4169, Q4170, Q4171, Q4173, Q4174, Q4175, Q4176, Q4177, Q4178, Q4179, Q4180, Q4181, Q4182, Q4199, Q4205, Q4206, Q4208, Q4209, Q4210, Q4211, Q4214, Q4215, Q4216, Q4217, Q4218, Q4219, Q4220, Q4221, Q4222, Q4224, Q4225, Q4227, Q4228, Q4229, Q4230, Q4231, Q4232, Q4233, Q4234, Q4235, Q4236, Q4237, Q4238, Q4239, Q4244, Q4245, Q4246, Q4247, Q4248, Q4249, Q4250, Q4251, Q4252, Q4253,Q4254, Q4255, Q4256, Q4257, Q4258, Q4259, Q4260, Q4261, Q4262, Q4263, Q4264, Q4265, Q4266, Q4267, Q4268, Q4269, Q4270, Q4271, Q4272, Q4273, Q4274, Q4275, Q4276, Q4277, Q4278, Q4280, Q4281, Q4282, Q4283, Q4284
  ​
  
   
• Hair transplant
  
  15775, 15776
   

• Keloid removal
  
  13100, 13101, 13102, 13120, 13121, 13122, 13131, 13132, 13133, 13151, 13152, 13153, 14000, 14001, 14020, 14021, 14040, 14041, 14060, 14061, 14301, 14302, 15002, 15003, 15004, 15005, 15040, 15050, 15100, 15101, 15110, 15111, 15115, 15116, 15120, 15121, 15130, 15131, 15135, 15136, 15150, 15151, 15152, 15155, 15156, 15157, 15200, 15201, 15220, 15221, 15240, 15241, 15260, 15261, 15271, 15272, 15273, 15274, 15275, 15276, 15277, 15278, 15570, 15572, 15574, 15576, 15600, 15610, 15620, 15630, 15650, 15731, 15733, 15734, 15736, 15738, 15740, 15750, 15756, 15757, 15758, 15760, 15770, 15780, 15781, 15782, 15783, 15786, 15787, 31830
   
• Lipectomy, liposuction, or any other excess fat-removal procedure
  
  15832, 15833, 15834, 15835, 15836, 15837, 15838, 15839, 15876, 15877, 15878, 15879
   
• Otoplasty
  
  13151, 13152, 13153, 14060, 14061, 15260, 15261, 21235, 69300, 69399
   
• Rhinoplasty
  
  30400, 30410, 30420, 30430, 30435, 30450
   
• Rhytidectomy
  
  15824, 15825, 15826, 15828, 15829, 15838, 15839, 15876
   
• Scar revision
  
  13100, 13101, 13102, 13120, 13121, 13122, 13131, 13132, 13133, 13151, 13152, 13153, 14000, 14001, 14020, 14021, 14040, 14041, 14060, 14061, 14301, 14302, 15002, 15003, 15004, 15005, 15040, 15050, 15100, 15101, 15110, 15111, 15115, 15116, 15120, 15121, 15130, 15131, 15135, 15136, 15150, 15151, 15152, 15155, 15156, 15157, 15200, 15201, 15220, 15221, 15240, 15241, 15260, 15261, 15271, 15272, 15273, 15274, 15275, 15276, 15277, 15278, 15570, 15572, 15574, 15576, 15600, 15610, 15620, 15630, 15650, 15731, 15733, 15734, 15736, 15738, 15740, 15750, 15756, 15757, 15758, 15760, 15770, 15780, 15781, 15782, 15783, 15786, 15787, 31830
   
• Skin closures
  
  13100, 13101, 13102, 13120, 13121, 13122, 13131, 13132, 13133, 13151, 13152, 13153, 14000, 14001, 14020, 14021, 14040, 14041, 14060, 14061, 14301, 14302, 15002, 15003, 15004, 15005, 15040, 15050, 15100, 15101, 15110, 15111, 15115, 15116, 15120, 15121, 15130, 15131, 15135, 15136, 15150, 15151, 15152, 15155, 15156, 15157, 15200, 15201, 15220, 15221, 15240, 15241, 15260, 15261, 15271, 15272, 15273, 15274, 15275, 15276, 15277, 15278, 15570, 15572, 15574, 15576, 15600, 15610, 15620, 15630, 15650, 15731, 15733, 15734, 15736, 15738, 15740, 15750, 15756, 15757, 15758, 15760, 15770
   
• Surgery for varicose veins, including perforators and sclerotherapy
  

​​​36465, 36466, 36470, 36471, 36475, 36476, 36478, 36479, 37500, 37700, 37718, 37722, 37735, 37760, 37761, 37765, 37766, 37780, 37785, 37799

Elective (nonemergency) gr​​​ound, air, and sea ambulance transportation, including inpatient hospital-to-hospital transfers

Outpatient private-duty nu​rsing

Day rehabilitation progr​​ams

Outpatient radiation ​​therapy

Radiology

• CT 
  
• CTA 
• Echocardiography services
  
• Testing transthoracic echocardiography (TTE) 
• Stress echocardiography (SE) 
• Transesophageal echocardiography (TE)
• MRA 
• MRI 
• Nuclear cardiology 
• ​PET scans 

Prosthetics/orthoses​​​ including: 

• Custom ankle-foot orthoses
  
  L1900, L1904, L1907, L1920, L1940, L1945, L1950, L1960, L1970, L1980, L1990, L2106, L2108, L4631​
   
• Custom knee-ankle-foot orthoses
  
  L2000, L2005, L2010, L2020, L2030, L2034, L2036, L2037, L2038, L2126, L2128
   
• Custom knee braces
  
  L1834, L1840, L1844, L1846, L1860
   
• ​Custom limb prost​hetics including accessories/components
  

K1014, K1022​, L5010, L5020, L5050, L​​5060, L5100, L5105, L5150, L5160, L5200, L5210, L5220, L5230, L5250, L5270, L5280, L5301, L5312, L5321, L5331, L5341, L5510, L5520, L5530, L5535, L5540, L5560, L5570, L5580, L5585, L5590, L5595, L5600, L5610, L5611, L5613, L5614, L5616, L5617, L5618, L5620, L5622, L5624, L5626, L5628, L5629, L5630, L5631, L5632, L5634, L5636, L5637, L5638, L5639, L5640, L5642, L5643, L5644, L5645, L5646, L5647, L5648, L5649, L5650, L5651, L5652, L5653, L5654, L5655, L5656, L5658, L5661, L5665, L5666, L5668, L5670, L5671, L5672, L5673, L5676, L5677, L5678, L5679, L5680, L5681, L5682, L5683, L5684, L5685, L5686, L5688, L5690, L5692, L5694, L5695, L5696, L5697, L5698, L5699, L5700, L5701, L5702, L5703, L5704, L5705, L5706, L5707, L5710, L5711, L5712, L5714, L5716, L5718, L5722, L5724, L5726, L5728, L5780, L5781, L5782, L5785, L5790, L5795, L5810, L5811, L5812, L5814, L5816, L5818, L5822, L5824, L5826, L5828, L5830, L5840, L5845, L5848, L5850, L5855, L5856, L5857, L5858, L5859, L5910, L5920, L5925, L5930, L5940, L5950, L5960, L5962, L5964, L5966, L5968, L5970, L5971, L5972, L5973, L5974, L5975, L5976, L5978, L5979, L5980, L5981, L5982, L5984, L5985, L5986, L5987, L5988, L5990, L5999, L6000, L6010, L6020, L6050, L6055, L6100, L6110, L6120, L6130, L6320, L6350, L6360, L6370, L6400, L6450, L6500, L6550, L6570, L6580, L6582, L6584, L6586, L6588, L6590, L6600, L6605, L6610, L6611, L6615, L6616, L6620, L6621, L6623, L6624, L6625, L6628, L6629, L6630, L6632, L6635, L6637, L6638, L6640, L6641, L6642, L6645, L6646, L6647, L6648, L6650, L6655, L6660, L6665, L6670, L6672, L6675, L6676, L6677, L6680, L6682, L6684, L6686, L6687, L6688, L6689, L6690, L6691, L6692, L6693, L6694, L6695, L6696, L6697, L6698, L6703, L6704, L6706, L6707, L6708, L6709, L6711, L6712, L6713, L6714, L6715, L6721, L6722, L6805, L6810, L6880, L6881, L6882, L6883, L6884, L6885, L6890, L6895, L6900, L6905, L6910, L6915, L6920, L6925, L6930, L6935, L6940, L6945, L6950, L6955, L6960, L6965, L6970, L6975, L7007, L7008, L7009, L7040, L7045, L7170, L7180, L7181, L7185, L7186, L7190, L7191, L7260, L7400, L7401, L7402, L7403, L7404, L7405, L7499

Selected durable medi​​​​cal equipment (DME) 

• Bone growth stimulators
  
  E0747, E0760
   
• Bone growth stimulator, electrical, noninvasive, spinal
  
  Precertification is performed by Carelon Medical Benefits Management, an independent company.  For additional information, refer to the current version of Medical Policy #00.01.66: Musculoskeletal Services.
   
• Bone-anchored (osseointegrated) hearing aids
  
  69716, 69719, 69726, 69727, L8690, L8691, L8692, L8693, L8694
   
• Continuous positive airway pressure (CPAP) devices, bi-level (Bi-PAP) devices, and all supplies
  
  Precertification is performed by Carelon Medical Benefits Management, an independent company.  To access the complete list of Carelon Sleep Disorder Management Diagnostic and Treatment Guidelines, click here.
   
• Dynamic adjustable and static progressive stretching devices (excludes CPMs)
  
  E1800, E1802, E1805, E1810, E1812, E1825, E1830
   
• Electric, power, and motorized wheelchairs including custom accessories
  
  E1002, E1003, E1004, E1005, E1006, E1007, E1008, E1009, E1010, E1012, E1239, E2291, E2292, E2293, E2294 E2310, E2311, E2312, E2313, E2321, E2322, E2323, E2324, E2325, E2326, E2327, E2328, E2329, E2330, E2331 E2340, E2341, E2342, E2343, E2351, E2368, E2369, E2370, E2373, E2374, E2375, E2376, E2377, E2603, E2604, E2605, E2606, E2607, E2608, E2609, E2613 E2614, E2615, E2616, E2617, E2620, E2621, E2622, E2623, E2624, E2625, E2626, E2627, E2628, E2629, E2630 K0010, K0011, K0012, K0013, K0014, K0056, K0108, K0813, K0814, K0815, K0816, K0820, K0821, K0822, K0823 K0824, K0825, K0826, K0827, K0828, K0829, K0835, K0836, K0837, K0838, K0839, K0840, K0841, K0842, K0843 K0848, K0849, K0850, K0851, K0852, K0853, K0854, K0855, K0856, K0857, K0858, K0859, K0860, K0861, K0862 K0863, K0864, K0890, K0891, K0898
   
• Insulin pumps
  
  E0784, E0787, S1034
   
• Manual wheelchairs with the exception of those that are rented
  
  E0958, E1002, E1003, E1004, E1005, E1006, E1007, E1008, E1009, E1010, E1012, E1031, E1037, E1038, E1039 E1050, E1060, E1070, E1083, E1084, E1085, E1086, E1087, E1088, E1089, E1090, E1092, E1093, E1100, E1110  E1130, E1140, E1150, E1160, E1161, E1170, E1171, E1172, E1180, E1190, E1195, E1200, E1220, E1221, E1222  E1223, E1224, E1229, E1231, E1232, E1233, E1234, E1235, E1236, E1237, E1238, E1240, E1250, E1260, E1270  E1280, E1285, E1290, E1295, E2291, E2292, E2293, E2294, E2295, E2603, E2604, E2605, E2606, E2607, E2608  E2609, E2613, E2614, E2615, E2616, E2617, E2620, E2621, E2622, E2623, E2624, E2625, E2626, E2627, E2628  E2629, E2630, K0001, K0002, K0003, K0004, K0005, K0006, K0007, K0008, K0009, K0108
   
• Negative pressure wound therapy
  
  A6550, A9272, E2402, K0743, K0744, K0745, K0746
   
• Neuromuscular stimulators
  
  E0744, E0745, E0764, E0770
   
• Power operated vehicles (POV)
  
  E1230, K0800, K0801, K0802, K0812
   
• Pressure reducing support surfaces including: 

• Air fluidized bed
  
  E0194
   
• Non powered advanced pressure reducing mattress
  
  E0371, E0373
   
• Powered air flotation bed (low air loss therapy)
  
  E0193, E0372
   
• Powered pressure reducing mattress
  
  E0277 

• Push rim activated power assist devices
  
  E0986
   
• Repair or replacement of all DME items, as well as orthoses and prosthetics that require precertification - See specific DME, orthoses, and prosthetics categories for Repair or Replacement codes that require precertification.
   
• Speech gen​erating devices
  

E2500, E2502, E2504, E2506, E2508, E2510, E2511, E2599, V5336

Medica​​​​l foods​

Hyperbaric oxygen therapy

In-Lab / Facility sleep studies

Proton beam ther​​apy

All transplant procedures, with the exception of corneal tra​nsplants

Mental health/serious mental illness/substa​​nce abuse

• Mental health and serious mental illness treatment (inpatient/partial hospitalization programs/intensive outpatient programs) 
• Repetitive transcranial magnetic stimulation (RTMS) 
• ​Substance abuse treatment (inpatient/partial hospitalization programs/intensive outpatient programs) 

Autism spectrum diso​​​rders 

• Applied behavioral analysis
  Precertifica​tion review for this service is provided by Magellan Healthcare, Inc. 

Genetic and genomic tests requiring ​​​precertification

Hereditary cancer syndrom​es 

• BRCA gene testing (breast and ovarian cancer syndrome) 
• Lynch syndrome gene testing 
• Familial adenomatous polyposis gene testing 
• PTEN gene testing (Cowden syndrome) 
• ​General cancer type panels (such as colon, breast, or neuroendocrine cancers) 

Hereditary heart dis​​eases 

• Long QT syndrome gene testing 
• ​Aortic dilation or a​neurysm syndrome testing (includes Marfan syndrome) 

Other full gene an​​alysis testing 

• Cystic fibrosis full gene sequencing and deletion/duplication analysis 
• ​PMP22 full gene sequencing and deletio​n/duplication analysis (Charcot-Marie-Tooth, hereditary neuropathy) 

Tests for many genetic disorders simultane​​ously 

• Expanded carrier screening panels (such as Carrier Status DNA Insight®, Counsyl Family Prep Screen, Pan-Ethnic Carrier Screening) 
• Hearing loss panels 
• Intellectual disability panels 
• Noonan spectrum diso​rders panels 

Specialty onc​​​​ology tests

• Cancer gene expression or protein signature tests (such as OncotypeDX®, MammaPrint®, Afirma®, Prosigna®, HeproDX™) 
• Tumor molecular profiling (such as FoundationOne®, neoTYPE™, OncoPlexDx®, and many others) 
• Tissue of origin testing (for cancer of unknown primary) 
• ​PCA3 testing for prostate cancer 

Pharmacogenomic tes​​ts 

• Cytochrome P450 metabolism gene testing (CYP2D6, CYP2C9, CYP2C19) 
• Specialized drug response gene panels (such as Assurex GeneSight®, GeneTrait, Genecept®, Millennium PGT^SM) 
• Warfarin response testing 
• ​MGMT methylati​on analysis for glioblastoma 

Other specialty​​​ tests 

• Coronary artery disease risk testing (such as CorusCAD®, CardioIQ®, APOE, ACE, KIF6) 
• ​Heart disease risk testing (such as CorusCAD®, CardioIQ®, APOE, ACE, KIF6, MTHFR) 

Geno​​​me-wide tests 

• Microarray studies 
• Whole exome testing 
• Whole genome testing 
• ​Mitochondrial genome or nuclear testing 

ANY genetic test for more than one gene or c​​​ondition (often includes words like “panel" or “comprehensive" in the name) 

ANY genetic test that will be billed with a ​​non-specific procedure code 

• Billed with CPT® codes 81400-81408 
• Billed with an unlisted code: 81479, 81599, 84999

Specialty drugs requiring pr​​ecertification

Amyotrophic Lateral Sclerosis agents

• Radicava™ - J1301
• Qalsody™ - J3490, J3590, and C9399​

Antineoplastic ag​​ents 

• Abraxane® - J9264
• Adstiladrin® - J9029​
  
• Adcetris® - J9042
• Alimta® - J9305
• Alymsys® - Q5126 (Note: Ophthalmologic use of Alymsys does not require precertification.)​
• Avastin® - C9257 and J9035 (Note: Opthalmologic use of Avastin does not require precertification. Precertification requirements apply to all FDA-approved biosimilars to this originator product.)
• Azedra®​* - A9590
• Blincyto™ - J9039
• Cyramza® - J9308
• Darzalex™ - J9145
• Darzalex Faspro™ – J9144
• Elahe​re™ - J9063
  
• Enhertu® - J9358
• Epkinly™ - C9155​
• Erbitux® - J9055
• Erwinaze® - J9019
• Herceptin® - J9355 (Precertification requirements apply to all FDA-approved biosimilars to this originator product.)
• Herceptin® Hylecta - J9356
• Herzuma® - Q5113
• ​Imjudo® - J9347​
• Kadcyla® - J9354
• Kanjinti™ - Q5117
• Kimmtrak® - J9274
• Kyprolis® - J9047
• Lumoxiti™ - J9313
• Lunsumio™ - J9350​
  
• Margenza™ - J9353
• Monjuvi® - J9349​​
• Mvasi™ - Q5107 (Note: Opthalmologic use of Mvasi does not require precertification.)
• Ogivri™ - Q5114
• Ontruzant® - Q5112
• Opdualag™ - J9298
• Oportuzumab Monatox (pending FDA approval) - J3490, J3590, and C9399​
• Paclitaxel - J9259
• Padcev™- J9177
• Pemetrexed - J9322, J9323
• Pemfexy™ - J9304, J9314, J9294, J9296 and J9297
  
• Perjeta® - J9306
• Phesgo™​ – J9316
• Pluvicto™* - J3490 and C9399​
• Polivy™ - J9309
• Poteligeo® - J9204
• Provenge® - Q2043
• Riabni™ - Q5123
• Rituxan® - J9312 (Precertification requirements apply to all FDA-approved biosimilars to this originator product.)
• Rituxan Hycela™ - J9311
• Ruxience™ - Q5119
• Rybrevant™ – J9061​
• Rylaze™ - J9021​
  
• Sarclisa® - J9227
• SH-111 (pending FDA approval) - J3490, J3590, and C9399​
• Taclantis (pending FDA approval) - J3490 and C9399
• Tecvayli™ - J9380 
  
• ​Tivdak™ - J9273
• Trazimera™ - Q5116
• Trodelvy™ - J9317
• Truxima™ - Q5115
• Vegzelma® - Q5129 (Note: Ophthalmologic use of Vegzelma does not require precertification.)​
  
• Xofigo®* - A9606
• Yervoy™ - J9228
• Zepzelca™ ​ – J9223
• Zevalin®* - A9543
• Zirabev™ - Q5118 (Note: Ophthalmologic use of Zirabev does not require precertification.)​
• Zynlonta™ J9359
• Zynyz™ - ​J9345​
  

 
* Prec​ertification review is provided by CareCore National, LLC d/b/a eviCore healthcare (eviCore). To access the eviCore website, click here. 

Anti PD-1/PD-L1 human monoclonal antibodies

• ​Balstilimab (pending FDA approval) - J3490, J3590, and C9399
  
• Bavencio® - J9023
  
• Imfinzi™ - J9173
  
• Jemperli™ - J9272
  
• Keytruda™ - J9271
  
• Libtayo® - J9119
  
• Opdivo® - J9299
  
• Penpulimab (pending FDA approval) - J3490, J3590, and C9399
• Sintilimab (pending FDA approval) - J3490, J3590, and C9399
  
• Tecentriq™ - J9022​
• Tislelizumab (pending FDA approval) - J3490 and C9399
• Toripalimab (pending FDA approval) - J3490 and C9399​
• Zynyz™ - J3590 and C9399​
  

Bone-modifying a​​gents 

• Evenity™ - J3111
• Prolia® - J0897
• ​Xgeva® - J0897 

Botulinum toxin agent​​s 

• ​Botox® - J0585 ​

Chemotherapy-induced n​​​ausea and vomiting (CINV) agents

• ​Sustol® - J1627 

Chimeric antigen receptor (CAR-T) thera​​pies

• Abecma® - Q2055
  
• ​Breyanzi® - Q2054
• Carvykti™ - Q2056
• Kymriah™ - Q2042
• Tecartus™ - Q2053​
• ​Yescarta™ - Q2041 
• ​​Chimeric antigen receptor t-cell (car-t) therapy; car-t cell administration, autologous – 0540T​​
  

Endocrine/m​​etabolic agents ​

• Achtar H.P.® - J0801 and J0802​
• Cosyntropin depot (pending FDA approval) - J3490, J3590, and C9399
• lanerotide - J1932
  
• Lutathera®* - A9513 and A9699
• Makena® - J1726 and J1729
• Sandostatin® LAR - J2353
• Somatuline® depot - J1930 
• Xenpozyme™ - J0218

Enzyme replacement agen​​​ts

• Aldurazyme® - J1931
• Brineura™ - J0567
• Cerezyme® - J1786
• Cipaglucosidase Alfa (pending FDA approval) – J3490, J3590, and C9399​
• Elaprase® - J1743
• Elelyso® - J3060
• Fabrazyme® - J0180
• Kanuma® - J2840
• Lumizyme® - J0221
• Mepsevii™ - J3397
• Naglazyme® - J1458
• Nexviazyme™ - J0219
• Pegunigalsidase Alfa (pending FDA approval) – J3590
• Replagal® (pending FDA approval) - J3490  
• Revcovi™ - J3590 and C9399
• Vimizim™ - J1322
• ​VPRIV® - J3385 
• Xenpozyme® - J3590 and C9399​

Gene Replacement / Gene Editing Therapies

• Hemgenix® - J1411​
  
• Luxturna™ - J3398​
  
• Roctavian™ - J3590 and C9399​
• Skysona® - J3590 and C9399​
• Vyjuvek™ - J3590 and C9399​
• Zolgensma® - J3399
• ​Zynteglo® - J3590 and C9399​
  
  
  

Hemophilia/Coagulation fac​​tors

• Advate® - J7192
• Adynovate® - J7207
• Afstyla® - J7210
• Alphanate® - J7186
• Alphanine SD® - J7193
• Alprolix® - J7201
• Altuviiio™ - J7214​
• Bebulin VH® - J7194
• Benefix® - J7195
• Coagadex® - J7175
• Corifact® - J7180
• Eloctate® - J7205
• Esperoct® - J7204
• Feiba NF® - J7198
• Feiba VH® - J7198
• Fibryga® - J7177
• Helixate FS® - J7192
• Hemlibra® - J7170
• Hemofil-M® - J7190
• Humate-P® - J7187
• Hyate-C® - J7191
• Idelvion® - J7202
• Ixinity® - J7213
• Jivi® - J7199 and J7208
• Koate-DVI® - J7190
• Kogenate FS® -J7192
• Kovaltry® - J7207 and J7211
• Monoclate-P® - J7190
• Mononine® - J7193
• Novoeight® - J7182
• Novoseven RT® - J7189
• Novoseven® - J7189
• Nuwiq® - J7209
• Obizur® - J7188
• Profilnine SD® - J7194
• Rebinyn® - J7203
• Recombinate®​ - J7192
• RiaSTAP® - J7178
• Rixubis® - J7195 and J7200
• Sevenfact® – J7212
• Tretten® - J7181
• Vonvendi® - J7179 and J7199
• Wilate® - J7183
• ​Xyntha® - J7185 

Hyaluronate acid​​​ products 

• Cingal (pending FDA approval) - J3490
• Durolane® - J7318
• Euflexxa™ - J7323
• Gel-One® - J7326
• Gelsyn-3™ - J7328
• GenVisc 850® - J7320
• Hyalgan® - J7321
• Hymovis® - J7322
• Supartz® - J7321
• Synojoynt™ - J7331
• Triluron™ - J7332
• TriVisc™ - J7329
• ​VISCO-3® - J7321

Immunologica​​l agents 

• Actemra® IV - J3262
• Avsola™ - Q5121
• Benlysta® IV - J0490
• Entyvio™ - J3380
• Ilumya™ - J3245
• Inflectra™ - Q5103
• Infliximab (unbranded) – J1745​
• Ixifi™ - Q5109
• Orencia® IV- J0129
• Remicade® - J1745 (Precertification requirements apply to all FDA-approved biosimilars to this originator product.)
• Renflexis™ - Q5104
• Saphnelo™ - J0491
• Simponi® Aria - J1602
• Skyrizi® IV - J2327
• Spevigo® - J1747
  
• Stelara® - J3357 and J3358  

Intravenous Immune Globulin/Su​​bcutaneous Immune Globulin (IVIG/SCIG)

• Intravenous Immune Globulin (IVIG) 

• Asceniv® - J1554
• Bivigam® - J1556
• Flebogamma® - J1572
• Flebogamma-Dif® - J1572
• Gammagard Liquid® - J1569
• Gammagard S/D® - J1566
• Gammaked® - J1561
• Gammaplex® - J1557
• Gamunex-C® - J1561
• Octagam® - J1568
• Panzyga® - J1576
• Privigen® - J1459 

• Subcutaneous Immune Globulin (SCIG)
  

• Cutaquig® - J1551
• Cuvitru® - J1555
• Hizentra® - J1559
• Hyqvia® - J1575
• ​​Xe​​​mbify® - J1558 

Multiple​ scleros​is ​agents

• ​Briumvi™ - J2329
  
• Lemtrada® - J0202
• Ocrevus™ - J2350
• ​Ty​sabri® - J2323 

Neutropenia

• Efbemalenograstim Alfa (pending FDA approval) - J3490, J3590, and C9399
• Fulphila™ - Q5108
• Fylnetra® - Q5130​
• Lapelga (pending FDA approval) - J3490, J3590, and C9399
• Neulasta® - J2506 (Precertification requirements apply to all FDA-approved biosimilars to this reference product.)
• Neulasta Onpro™ - J2505 J2506
• Neupogen® - J1442
• Nivestym™ - Q5110
• Nyvepria™ - Q5122
• Plinabulin (pending FDA approval) - J3490, J3590, and C9399
• Releuko™ - Q5125
• Rolvedon™ - J1449​
• Stimufend® - Q5127
  
• Udenyca™ - Q5111
• Ziextenzo® - Q5120

Ophthalmi​​​c agents 

• Abicipar (pending FDA approval) - J3490, J3590, and C9399
• Beovu® - J0179
  
• Byooviz™ - Q5124
• Cimerli™ - Q5128​
• Eylea® - J0178 (Precertification requirements apply to all FDA-approved biosimilars to this reference product.)​
  
• ​​Eylea® HD – J3590 and C9399​
  
• Lucentis® - J2778 (Precertification requirements apply to all FDA-approved biosimilars to this reference product.)
• Susvimo™- C2779
  
• Tepezza® - J3241
• Vabysmo® - J2777

​
​

Pulmonary arterial hyperten​​​sion

• Flolan® - J1325
• Remodulin® - J3285
• Revatio® - J3490 and C9399
• Trevyent (pending FDA approval) - J3490 and C9399
• Tyvaso® - J7686
• Veletri® - J1325
• Ventavis® - Q4074 

Respiratory ag​​​ents 

• Cinqair® - J2786
• Synagis® - 90378
• Tezspire™ - J2356​
• ​Xolair® - J2357 

Respiratory enzyme​​s (Alpha-1 antitrypsin)

• Aralast - J0256
• Glassia™ - J0257
• Prolastin® - J0256
• ​Zemaira® - J0256 

Miscellaneous therapeuti​​​c agents 

• Adakveo® - J0791
• Ampligen® (pending FDA approval) - J3490
• Amvuttra™ - J0225​
• Cosela® - J1448​
• Crysvita® - J0584
• Donislecel (pending FDA approval) – J3490, J3590, and C9399​
• Enjaymo™ - J1302
• Evkeeza™ - J1305
• Exenatide sustained-release ITCA 650 (pending FDA approval) - J3490
• Gamifant® - J9210
• Givlaari® - J0223
• Ilaris® - J0638
• Krystexxa® - J2507
• Leqvio® - J1306​
• Narsoplimab (pending FDA approval) - C9399 and J3590​
• Onpattro® - J0222
• Oxlumo™ – J0224
• Reblozyl® - J0896
• Remune (pending FDA approval) - J3490
• Rethymic™ - J3590, and C9399
• Soliris® - J1300 (Precertification requirements apply to all FDA-approved biosimilars to this originator product.)
• Spinraza™ - J2326
• ​​Tzield™ - J9381​
  
• Ultomiris™ - J1303
• Uplizna™ – J1823
• Vyepti™ - J3032
• Vyvgart™ - J9332​​
• ​Vyvgart® Hytrulo – J3590 and C9399​
• Xiaflex® – J0775 

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